SA视讯> 社区> 出国考试> 国际趣闻> 新研究:想得太多,死得越快(双语)

  One key to a longer life could be a quieter brain without too much neural activity, according to a new study that examined postmortem brain tissue from extremely long-lived people for clues about what made them different from people who died in their 60s and 70s.


SA视讯   "Use it or lose it" has dominated thinking on how to protect the aging brain, and extensive research shows there are many benefits to remaining physically and mentally active as people get older.


  But the study, published in the journal Nature, suggests more isn't always better. Excessive activity - at least at the level of brain cells - could be harmful.

SA视讯   但发表在《自然》杂志上的这项研究表明,并不总是越多越好。至少过度的脑细胞活动可能是有害的。

SA视讯   "The completely shocking and puzzling thing about this new paper is … [brain activity] is what you think of as keeping you cognitively normal. There's the idea that you want to keep your brain active in later life," said Michael McConnell, a neuroscientist at the Lieber Institute for Brain Development, who was not involved in the study.

SA视讯   “这篇新论文最让人震惊和困惑的是……(大脑活动)就是你所认为的能让你保持正常认知的事物。而你希望在日后的生活中保持大脑活跃,”利伯尔大脑发育研究所神经学家迈克尔·麦康奈尔说道,他并没有参与这项研究。

  "The thing that is super unexpected is … limiting neural activity is a good thing in healthy aging. It's very counterintuitive."


SA视讯   Researchers at Harvard Medical School analyzed brain tissue donated to human brain banks by people ranging in age from their 60s and 70s to centenarians who lived to be 100 or older.

SA视讯   哈佛大学医学院的研究人员分析了60多岁、70多岁到100多岁的老人捐献给人类大脑库的脑组织。

SA视讯   They found people who died before their mid-80s had lower levels in their brains of a protein called REST that tamps down genes involved in sparking brain activity, compared to the very oldest people. REST had already been shown to be protective against Alzheimer's disease.